BİOMATBIOMATERIALS AND TISSUE ENGINEERING RESEARCH LABORATORY


Biosensors

 

Construction of a biosensor is based on inhibition of a biological activity by the analyte. Acetylcholinesterase (AChE) is one of the biosensitive agents attached to the biosensor for the detection of pesticides with anti-cholinesterase activity (eg. carbamates and organophosphates). Examples include membranes made of poly(2-hydroxyethylmethacrylate) (pHEMA) being used as the matrix for the immobilization of acetylcholinesterase and choline oxidase. Quantitative determination is based on the decrease in oxygen consumption in pesticide presence.